I can remove it easily from Windows machine by changing some Registry values whereas in Mac its quite different. You can follow the list to delete or uninstall app on Mac effortlessly. This vid explains how to Uninstall Skype for Business for Mac manually.
Select Personal, then un-select Automatically start the app when I log on to Windows and Start the app in the foreground. The steps to uninstall Skype for Business are almost the same as for the regular version of Skype. By default, they should be located in the system. This cmdlet was introduced in Skype for Business Server 2015 Cumulative Update 6 (December 2017). Press Control and click at the same time. Yes, please restart your Mac to check it. In this way, you can easily uninstall Office, Safari, Viber, etc., from Mac. I looked for the settings but the tag for start up was not set. Visit Business Insider's homepage for more stories. See How to Perform a Clean Uninstall of Lync for Mac 2011 for more information. To be clear, this isn't Skype I'm talking about, but Skype for Business.